In Once Human, your power in combat is determined by your equipment and weaponry. A well-coordinated build is essential, whether you're facing corrupted creatures in PvE or assaulting player bases in PvP.
This guide details four of the top-performing builds in the current meta, breaking down recommended weapons, gear modifications, synergies, and tactical advice. Each loadout, from area-of-effect specialists to damage-over-time and critical hit builds, has been proven effective for solo and cooperative play.
New players should start with our comprehensive Once Human Beginner's Guide for foundational knowledge.
Final Tips for Optimizing Your Build
Synchronize Weapon and Mod Effects: Select gear modifications that specifically amplify your weapon's elemental traits or status effects.Prioritize Upgrades: Never underestimate the power boost from higher rarity and enhancement levels—avoid using obsolete gear.Prepare Alternate Loadouts: Maintain a secondary build with a different damage type to counter specific mutant resistances or PvP strategies.
Each build excels in specific situations, be it single-target boss encounters, clearing hordes of enemies, or quick PvP eliminations. Test each setup, adjust your modifications, and switch strategies based on your objectives or enemy vulnerabilities.
For the optimal gaming experience—with precise aiming, efficient multi-instance farming, and swift inventory management—play Once Human on BlueStacks. Enhance your performance with full controller support and consistently high frame rates.
